Probiotics

Before healthcare products keep people safe, it’s necessary to keep the products themselves safe!

Whether oral solid dosage pharmaceuticals, drug delivery systems or diagnostic and medical devices, many healthcare products are susceptible to degradation and stability issues.

Airnov is the specialist of controlled atmosphere with deep knowledge in moisture, oxygen and odors management inside healthcare packaging. Contact us for more details on which solution is the most suitable for your specific needs.

Probiotics

Probiotics are live yeasts and bacteria – microorganisms that aim to restore the human gut flora and improve overall health. The way probiotics are administered can vary widely – from liquids to powders to capsules. Due to their sensitive nature, probiotics need quality packaging in order to prevent external factors from interfering with their properties. Airnov offers a selection of options – from Pharmakeep® oxygen absorbers and Oxynov barrier bottles to plastics tubes and desiccant stoppers, canisters and packets. Our manufacturing facility allows for a seamless production process – with quality control being maintained throughout.

The benefits and challenges of the probiotics production process

Today, pharmacies and health food stores sell probiotics in the form of food products or dietary supplements. Created through the process of fermentation, they are available as yogurts, beverages, powders, and capsules. Their effects are gentle but, through repeated use, probiotics can have a distinctly beneficial effect on combating health issues from eczema and diarrhea. Probiotics are becoming increasingly popular and are one of the fastest growing segments of the nutraceutical industry.

The way probiotics work is not yet fully understood and there is still a good deal of debate over how potent their influence is. The basic idea rests on the fact that the human body naturally hosts two kinds of bacteria in its gut – one is deemed beneficial while others are considered harmful. If the ideal proportions between the two are thrown off balance and the number of harmful organisms exceeds the number of beneficial ones, a host of illnesses can occur. The immune system suffers and the body is unable to function as well as it should.

Probiotics are known to positively affect the host organism by improving the intestinal balance. Stimulating microbial growth, they allow beneficial microorganisms naturally occurring in the gut to thrive and perform their task. Probiotics also work on taking care of harmful bacteria and flushing them out of the body so that the balance is regained – and kept. There are several types available, namely Lactobacillus (found in common yogurt), Bifidobacterium (mostly in cheese) which helps with Irritable Bowel Syndrome (IBS), and Saccharomyces boulardii, a type of yeast that is able to help with constipation and general gastrointestinal discomfort. There is also evidence that they may improve overall immune health, thus preventing minor ailments such as the common cold.

The study of probiotics stretches back to 1907 when the Russian scientist Élie Metchnikoff proposed that yogurt and other kinds of fermented dairy products have the ability to replace harmful gut microbes with more beneficial flora. This idea was further expanded upon by the German Alfred Nissle. Probiotics are safe to consume and side-effects are extremely rare, mostly occurring due to bacteria host interactions.

The greatest risk brought about by the production process lies at the very end. Inadequate packaging can create more issues than perhaps any other segment. Moisture and oxygen seeping into containers can trigger unwanted chemical reactions. Oxidative degradation can occur quickly, rendering the product useless – if not harmful – in a matter of hours. It involves the disintegration of macromolecules brought about by the action of oxygen on the substrate. The appearance of unwanted odors is also quite common.

The ways to implement protective measures in a timely manner

Probiotics – today mostly sold as food products – tend to be even more delicate than common pharmaceutical stock. Extra care ought to be taken to ensure its preservation. Drawing on experience in healthcare as well as a heightened awareness of best practices in the food industry, Airnov is committed to always undertaking extensive research.

This ability to adapt is not limited to approaching different types of products. We are also able to address and commit to meeting all client needs. Geographic location is never an obstacle: we have 5 production facilities located strategically throughout the world. Each manufacturing facility meets is GMP certified for pharmaceutical packaging, and we use these same production lines and methods to produce high-quality moisture protection, oxygen scavenger, and odor control products for the nutraceutical and probiotics industries.

From Pharmakeep® oxyen absorber to desiccant packets

Probiotics, created through a fermentation process, often have a short shelf life. The role of packaging is to prolong it and prevent any unwanted changes to the product. Moisture, oxygen, and unpleasant odors all present issues for the product and the customer. Understanding the needs of each probiotic is key to developing a robust packaging system to ensure effective treatments for end users. All of our solutions meet industry standards and are designed to exceed your quality standards.

Pharmakeep® oxygen absorber contains polymer-based active material. The latest in oxygen control, they don’t require any sort of moisture in order to react and perform their role. Colloquially known as “oxygen scavengers”, the active materials protect solid products in primary packagings and liquids products in secondary packagings, guaranteeing full degradation avoidance.

Plastic tubes & desiccant stoppers are an excellent combo that performs proper control of MVTR (Moisture Vapor Transmission Rate) by applying a strict stage-gate process. Hinge closure provides consumer appeal, ergonomics, and prolonged protection. ADP® technology prevents dust from entering the container. Stoppers can also be filled with EQiusTM-Equilibrium stabilizers, regardless of whether they are being produced in Europe, Asia, and the United States. In addition, they are fully compliant with all US FDA and EU regulations.

Desiccant canisters are drop-in style sorbent components reliant on high-speed insertion. They can be hopper-fed and are able to meet specific stability requirements. Odor absorption properties are provided by active carbon while laser-marking artwork enables the creation of custom-marked canisters. Able to comply with US Pharmacopeia USP <670> standard, they remain cost-efficient and allow for full Business Continuity Planning (BCP).

Desiccant packets carry superior protective properties, help maintain stability, and are able to keep away moisture and ensure the expiration date is adhered to. Airnov’s CompatilusTM Program ensures full compatibility with various automatic desiccant inserters from key equipment manufacturers. Packets are available in a range of sizes – standard or customized – and also benefit from odor absorption properties.

The advantages of our approach

Since its inception as an integral part of Airsec in 1952, our company has provided clients from across the globe with reliable, trustworthy, efficient service. The products from our line are a testament to our commitment to providing only the best for our clients. We understand the challenges faced and use agility, experience, performance, and respect to create a perfect environment for progress. We are proud of our ability to adapt to change and face the future with a bright and assertive attitude. Through constant striving for innovation in packaging and protecting pharmaceutical products, medical devices, we aim for a level of safety rarely surpassed by our competitors.

Our Business Continuity Planning (BCP) enables us to utilize multi-lane production equipment at multiple sites, making sure that each order – no matter how large – is delivered at the right time. A fully transverse approach is perhaps our biggest advantage. We offer products in all ranges, being able to meet any demand. The team has a sharp eye for innovation and is committed to delivering only stellar results.

Get in touch

We at Airnov  are always open to new ideas, propositions, and business inquiries. If you have any questions, would like a quote for your next project, or simply wish to get more information on our extensive range of products – do not hesitate to contact us. We will do everything to take your ideas to the next level and work together to create the best solution to fit your needs.