Inhalation

Before healthcare products keep people safe, it’s necessary to keep the products themselves safe!

Whether oral solid dosage pharmaceuticals, drug delivery systems or diagnostic and medical devices, many healthcare products are susceptible to degradation and stability issues.

Airnov is the specialist of controlled atmosphere with deep knowledge in moisture, oxygen and odors management inside healthcare packaging. Contact us for more details on which solution is the most suitable for your specific needs.

Inhalation

In medicine, inhalation products typically target pharmaceuticals which have a beneficial effect on the functioning of the breathing mechanism (as in the case of asthma and chronic obstructive pulmonary disease). Still, inhalers are sensitive devices, susceptible to damage. This is where Airnov is able to step in and offer a host of solutions – from Pharmakeep® canisters, EQius™
Equilibrium RH stabilizer , ADP® (Advanced Desiccant Polymer) to desiccant packets. All comply with FDA guidance, as well as other international quality guidelines, and help keep inhalation therapy products secure and safe from moisture and other external factors.

Inhalation products - their benefits and risks

The cycle of breathing is an essential process. It is an integral part of human life and the way in which the body receives the oxygen needed to survive. Without it, practically no living thing would be able to function. Breathing is also one of the ways in which medication can be administered since the internal lining of the lungs is exceptionally absorbent, with inhalable medications dating back millennia to at least the time of Ancient Egypt. Aromatic and medicinal vapors were used in an attempt to heal various diseases – some successfully, others less so. In the dawn of the modern era, John Mudge created one of the first inhalers in 1778, followed by another patent by Beigel in 1866. Substances such as iodine, ammonia, and chlorine were first used but the list soon expanded to include numerous other drug compounds.

Today, inhalation products – also referred to as inhalers, allergy sprays, puffers, or pumps – are the most common way of delivering medicines into the lungs. An inhaler can be nasal or oral, each having its own unique advantages as well as disadvantages. These pharmaceutical products are an integral part of inhalation therapy for asthma, COPD, allergies, and a host of other disorders. Easy to use, safe, and effective, they have created a revolution in the field. With the proper education of the end-user, they can be employed daily and make the life of those suffering from certain illnesses a lot easier. Soft mist inhalers and nebulizers are available in pharmacies across the globe, but the dry powder inhalers and meter-dosed inhalers are the most popular by their facility of usage.

Still, much like all other devices, they come with a few innate issues. Dry inhalers are particularly to changes in relative humidity. When the humidity is too high, the particles tend to clump together, preventing the fine particles from effectively dispersing through the airway and delivering incomplete doses. When the humidity is too low, the particles tend to become charged and statically cling to the inside of the delivery device, also delivering ineffective or incomplete doses. Airnov’s Eqius™ products are designed to hold a stable humidity level that can be tailored to the device and the pharmaceutical being used.

Oxygen is another enemy of the inhaler. Penetrating into the core of the mechanism, it can diminish its ability to perform its task. Inadequate packaging can only aggravate these risks so a good deal of attention ought to be devoted to solving this problem before the inhaler is delivered to its destination.

The ways to follow quality guidelines and deliver excellent service

An inhaler – much like many other pharmaceutical products – is a sensitive medical device that can bring great relief to a patient. Its parts, however, are not created to withstand extreme conditions and only proper protection will guarantee that it remains intact until it is ready to be used. Packaging performs a vital role and Airnov remains committed to playing its part in this process. Our team is constantly researching new protective solution and only the most efficient and sustainable/durable/robust options make the final cut.

We always consider the advantages and disadvantages of every approach in order to select the best possible solution for each individual case. This way, we are able to tackle any challenge and come up with a logistics plan that will ensure a seamless transition, speed of delivery, and preservation of every item we are entrusted with. Through stability studies and superior quality control, we make sure that our products meet the highest standards and offer protection that meets and exceeds the demands of our clients.

Each product has its own protection

Keeping sensitive products safe and secure requires more than a couple of feats of engineering. Through extensive research and testing, Airnov offers products able to adapt to different conditions and provide protection of inhalation products in nearly all circumstances. They are divided into four types:

Pharmakeep® canisters are produced in the form of canisters, packets, and bags. They are able to protect pharmaceutical devices from oxygen degradation and oxidative reactions – without requiring any moisture to react. These canisters can easily be used in conjunction with desiccants, without any adverse effect on their functionality. They can also be paired with Airnov’s Oxynov® oxygen barrier for improved performance.

EQius™ are used to maintain predetermined humidity levels where such conditions are required – including different equilibrium levels from 10% to 60% RH. Equilibrium RH Stabilizers can fit the packaging of just about any nasal or oral inhaler and are fully able to comply with FDA guidance. They perform like humectants (disorders) and desiccants (adsorbers) and are ideal for the protection of sensitive formulations.

ADP® – Advanced Desiccant Polymer is able to address the needs of various moisture-sensitive medical devices. With careful planning and precise insertion, the ADP element becomes an integral part of the device. Embedded into the packaging, this active desiccant polymer solution is suited for pharmaceutical products. It is able to meet specific absorption requirements and performs permanent desiccation, is non-dusting, and guarantees swallowing avoidance.

Desiccant packets are a technology that has been around for decades but that has, due to efforts from the team at Airnov, been updated to meet the highest standards and the latest quality guidelines. Through research and stability studies, we have perfected a cost-efficient product that is comparable to most high-end solutions.

Our range of solutions are designed to be used independently or in conjunction to make sure that the inhalers reach those suffering from COPD and asthma intact.

The advantages of our approach

Since its inception as an integral part of Airsec in 1952, our company has provided clients from across the globe with reliable, trustworthy, efficient service. The products from our line are a testament to our commitment to providing only the best for our clients. We understand the challenges faced and use agility, experience, performance, and respect to create a perfect environment for progress. We are proud of our ability to adapt to change and face the future with a bright and assertive attitude. Through constant striving for innovation in packaging and protecting pharmaceutical products, medical devices, we aim for a level of safety rarely surpassed by our competitors.

Our Business Continuity Planning (BCP) enables us to utilize multi-lane production equipment at multiple sites, making sure that each order – no matter how large – is delivered at the right time. A fully transverse approach is perhaps our biggest advantage. We offer products in all ranges, being able to meet any demand. The team has a sharp eye for innovation and is committed to delivering only stellar results.

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We at Airnov are always open to new ideas, propositions, and business inquiries. If you have any questions, would like a quote for your next project, or simply wish to get more information on our extensive range of products – do not hesitate to contact us. We will do everything to take your ideas to the next level and work together to create the best solution to fit your needs.